I'm guessing this strand is alternating natural color and dyed freshwater pearls. Is there any difference in the level of the white area, or a noticable edge where the colors transition? Have you looked at the area through a loupe? For some reason this area didn't take the dye. It probably won't affect the wearability of the strand if the area is amooth.
A 10x loupe can be very helpful for checking all kinds of irregularities on pearls, looking down the hole to see nacre thickness, detangling knots if one strings pearls and so much more! Basic loupes are under $20.