I'm having the same problem with my hands. I can't work half my clasps anymore. I recently had some of my pearls restrung with big, chunky hooks. Toggles also work well, but make sure the bar is big enough that it doesn't slip out of the ring part. And you might want a bit of chain on the bar to make it easier to work, so you don't scratch the pearls.
I also find the large and small orbit clasps fairly easy to work. I have it on most of my pearls.